Use of Hexamethonium Bromide and Decamethonium Iodide with Electroplexy

Decamethonium iodide: a reappraisal.

DECAMETHONIUM iodide (CIO) was first described by Barlow and Ing, and by Paton and Zaimis, in 1948. The following year it was introduced into anaesthesia as a result of the work of Organe, and of Hewer, Lucas, Prescott and Rowbotham. Apart from the initial enthusiasm decamethonium has never found much favour with anaesthetists. In 1950 an editorial in the Lancet, comparing it with Gallamine, st...

Effects of hexamethonium and decamethonium on end-plate current parameters.

The effects of neuromuscular blocking concentrations of hexamethomum and decamethonium on end-plate current parameters have been studied in frog sartorius nervemuscle preparations. In the presence of either drug, hyperpolarization of the cell membrane reduces the peak amplitude of the end-plate current despite the increase in driving force. The effect is larger for hexamethonium than for decame...

The action of decamethonium iodide (C.10) in myasthenia gravis.

Myasthenia gravis is a chronic disease characterized by abnormal fatigue of the voluntary muscles. This fatigue is due to a progressive failure of conduction at the myoneural junction after muscle contraction, and can be temporarily relieved by prostigmine sulphate (Walker, 1934). The exact nature of the neuromuscular block remains obscure, and an analysis of neuromuscular transmission in myast...

Europium-doped barium bromide iodide

Single crystals of Ba(0.96)Eu(0.04)BrI (barium europium bromide iodide) were grown by the Bridgman technique. The title compound adopts the ordered PbCl(2) structure [Braekken (1932 ▶). Z. Kristallogr.83, 222-282]. All atoms occupy the fourfold special positions (4c, site symmetry m) of the space group Pnma with a statistical distribution of Ba and Eu. They lie on the mirror planes, perpendicul...

The hemodynamic effects of hexamethonium bromide in the dog, with special reference to splanchnic pooling.